Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.S673P

c.2017T>C

Surrounding Variants

1 paper

NM_000176.3

p.S673A

c.2017T>G

1 paper

NM_000176.3

p.L672L

c.2016C>T

14 papers

NM_000176.3

p.L672P

c.2015T>C

1 paper

NM_000176.3

p.L671_L672delFs

c.2013_2014delGA

1 paper

NM_000176.3

p.L670P

c.2009T>C

1 paper

NM_000176.3

p.L669F

c.2007A>T

1 paper

NM_000176.3

p.L669F

c.2007A>C

1 paper

NM_000176.3

p.C665S

c.1994G>C

1 paper

NM_000176.3

p.C665S

c.1993T>A

1 paper

NM_001204261.2

p.L567L

c.1701C>T

1 paper

NM_000176.3

p.Y663H

c.1987T>C

4 papers

NM_000176.3

p.Y660*

c.1980T>G