Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

38 papers

NM_000176.3

p.D641V

c.1922A>T

Surrounding Variants

1 paper

NM_000176.3

p.Q642E

c.1924C>G

1 paper

NM_000176.3

p.Y640S

c.1919A>C

1 paper

NM_000176.3

p.C643G

c.1927T>G

2 papers

NM_000176.3

p.C643R

c.1927T>C

1 paper

NM_000176.3

p.C643S

c.1927T>A

1 paper

NM_000176.3

p.C643S

c.1928G>C

1 paper

NM_000176.3

p.M639V

c.1915A>G

2 papers

NM_000176.3

p.C638S

c.1913G>C

2 papers

NM_000176.3

p.C638Y

c.1913G>A

1 paper

NM_000176.3

p.C638G

c.1912T>G

2 papers

NM_000176.3

p.C638S

c.1912T>A

1 paper

NM_000176.3

p.H645Y

c.1933C>T