Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.T562M

c.1685C>T

Surrounding Variants

2 papers

NM_000176.3

p.M560T

c.1679T>C

1 paper

NM_000176.3

p.M560L

c.1678A>T

1 paper

NM_000176.3

p.M560L

c.1678A>C

3 papers

NM_000176.3

p.M565R

c.1694T>G

36 papers

NM_000176.3

p.I559N

c.1676T>A

1 paper

NM_000176.3

p.M565K

c.1694T>A

4 papers

NM_000176.3

p.G567A

c.1700G>C

1 paper

NM_000176.3

p.T556T

c.1668T>G

1 paper

NM_000176.3

p.G568W

c.1702G>T

11 papers

NM_000176.3

p.T556I

c.1667C>T

1 paper

NM_000176.3

p.T556A

c.1666A>G

1 paper

NM_000176.3

p.R569W

c.1705C>T