Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_000176.3

p.T504S

c.1510A>T

Surrounding Variants

5 papers

NM_000176.3

p.T504S

c.1511C>G

1 paper

NM_000176.3

p.G506*

c.1516G>T

1 paper

NM_000176.3

p.G506R

c.1516G>A

8 papers

NM_000176.3

p.Q501H

c.1503G>T

8 papers

NM_000176.3

p.Q501H

c.1503G>C

1 paper

NM_000176.3

p.Q501R

c.1502A>G

1 paper

NM_000176.3

p.V507V

c.1521C>G

1 paper

NM_000176.3

p.T511A

c.1531A>G

2 papers

NM_000176.3

p.S512fs

c.1534_1535fs

1 paper

NM_000176.3

p.K495insFs

c.1484_1485insG

1 paper

NM_000176.3

p.T493S

c.1477A>T

1 paper

NM_000176.3

p.P515H

c.1544C>A