Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_000176.3

p.R491*

c.1471C>T

Surrounding Variants

1 paper

NM_000176.3

p.A490fs

c.1468_1469fs

1 paper

NM_000176.3

p.K492E

c.1474A>G

1 paper

NM_000176.3

p.K492R

c.1475A>G

1 paper

NM_000176.3

p.K492N

c.1476A>T

1 paper

NM_000176.3

p.K492N

c.1476A>C

1 paper

NM_000176.3

p.T493S

c.1477A>T

1 paper

NM_000176.3

p.K495insFs

c.1484_1485insG

4 papers

NM_000176.3

p.A490Splc

c.1469-16G>T

1 paper

NM_000176.3

p.Q501R

c.1502A>G

8 papers

NM_000176.3

p.Q501H

c.1503G>T

8 papers

NM_000176.3

p.Q501H

c.1503G>C

5 papers

NM_000176.3

p.T504S

c.1510A>T