Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000176.3

p.C476S

c.1426T>A

Surrounding Variants

2 papers

NM_000176.3

p.C476S

c.1427G>C

3 papers

NM_000176.3

p.C476W

c.1428C>G

11 papers

NM_000176.3

p.R477C

c.1429C>T

1 paper

NM_000176.3

p.R477G

c.1429C>G

17 papers

NM_000176.3

p.R477S

c.1429C>A

1 paper

NM_000176.3

p.R477L

c.1430G>T

1 paper

NM_000176.3

p.R477P

c.1430G>C

52 papers

NM_000176.3

p.R477H

c.1430G>A

1 paper

NM_000176.3

p.P474R

c.1421C>G

10 papers

NM_000176.3

p.Y478C

c.1433A>G

1 paper

NM_000176.3

p.C473S

c.1418G>C

1 paper

NM_000176.3

p.C473G

c.1417T>G