Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.R366G

c.1096A>G

Surrounding Variants

1 paper

NM_000176.3

p.N365S

c.1094A>G

1 paper

NM_000176.3

p.C367S

c.1099T>A

1 paper

NM_000176.3

p.C367S

c.1100G>C

1 paper

NM_000176.3

p.Q368*

c.1102C>T

1 paper

NM_000176.3

p.N363I

c.1088A>T

334 papers

NM_000176.3

p.N363S

c.1088A>G

1 paper

NM_000176.3

p.G369A

c.1106G>C

1 paper

NM_000176.3

p.E362K

c.1084G>A

1 paper

NM_000176.3

p.G371*

c.1111G>T

1 paper

NM_000176.3

p.N374D

c.1120A>G

1 paper

NM_000176.3

p.N374S

c.1121A>G

1 paper

NM_000176.3

p.N374K

c.1122C>A