Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.P349L

c.1046C>T

Surrounding Variants

1 paper

NM_000176.3

p.L341H

c.1022T>A

1 paper

NM_000176.3

p.S340C

c.1019C>G

1 paper

NM_000176.3

p.N337S

c.1010A>G

1 paper

NM_000176.3

p.N337fs

c.1009_1010fs

2 papers

NM_000176.3

p.M336fs

c.1006_1007fs

1 paper

NM_000176.3

p.E362K

c.1084G>A

1 paper

NM_000176.3

p.D335Fs

c.1003delinsGAFs

1 paper

NM_000176.3

p.N363I

c.1088A>T

334 papers

NM_000176.3

p.N363S

c.1088A>G

1 paper

NM_000176.3

p.N365S

c.1094A>G

1 paper

NM_000176.3

p.Y332*

c.996C>G

1 paper

NM_000176.3

p.Y332*

c.996C>A