Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.I292F

c.874A>T

Surrounding Variants

1 paper

NM_000176.3

p.I292N

c.875T>A

1 paper

NM_000176.3

p.V291fs

c.871_872fs

1 paper

NM_000176.3

p.K293R

c.878A>G

1 paper

NM_000176.3

p.G290insFs

c.869_870insA

1 paper

NM_000176.3

p.G290A

c.869G>C

3 papers

NM_000176.3

p.K293K

c.879G>A

1 paper

NM_000176.3

p.G290E

c.869G>A

5 papers

NM_000176.3

p.T288N

c.863C>A

1 paper

NM_000176.3

p.T288A

c.862A>G

1 paper

NM_000176.3

p.L286L

c.858C>T

1 paper

NM_000176.3

p.L286L

c.858C>A

1 paper

NM_000176.3

p.L286P

c.857T>C