Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.K280N

c.840A>T

Surrounding Variants

1 paper

NM_000176.3

p.K280K

c.840A>G

1 paper

NM_000176.3

p.E279G

c.836A>G

1 paper

NM_000176.3

p.D282D

c.846T>C

2 papers

NM_000176.3

p.K277R

c.830A>G

1 paper

NM_000176.3

p.I284V

c.850A>G

2 papers

NM_000176.3

p.K277E

c.829A>G

2 papers

NM_000176.3

p.E285*

c.853G>T

1 paper

NM_000176.3

p.V276M

c.826G>A

1 paper

NM_000176.3

p.E285E

c.855A>G

1 paper

NM_000176.3

p.L286F

c.856C>T

1 paper

NM_000176.3

p.L286P

c.857T>C

1 paper

NM_000176.3

p.L286L

c.858C>T