Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.F235L

c.703T>C

Surrounding Variants

1 paper

NM_000176.3

p.S234L

c.701C>T

1 paper

NM_000176.3

p.F235L

c.705C>G

1 paper

NM_000176.3

p.S234*

c.701C>G

1 paper

NM_000176.3

p.F235L

c.705C>A

1 paper

NM_000176.3

p.S234*

c.701C>A

1 paper

NM_000176.3

p.L236V

c.706C>G

1 paper

NM_001204260.2

p.D144Fs

c.431delinsAGFs

1 paper

NM_000176.3

p.L236P

c.707T>C

1 paper

NM_000176.3

p.L236L

c.708T>C

1 paper

NM_001204260.2

p.D144fs

c.430_431fs

6 papers

NM_000176.3

p.D233N

c.697G>A

1 paper

NM_000176.3

p.D232G

c.695A>G