Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.E207A

c.620A>C

Surrounding Variants

1 paper

NM_000176.3

p.G205D

c.614G>A

2 papers

NM_000176.3

p.E210Q

c.628G>C

1 paper

NM_000176.3

p.S211R

c.631A>C

2 papers

NM_000176.3

p.E210delFs

c.630delC

11 papers

NM_000176.3

p.S203A

c.607T>G

1 paper

NM_000176.3

p.S211R

c.633T>G

3 papers

NM_000176.3

p.S203P

c.607T>C

1 paper

NM_000176.3

p.S211R

c.633T>A

1 paper

NM_000176.3

p.G202G

c.606G>A

1 paper

NM_000176.3

p.W213R

c.637T>C

1 paper

NM_000176.3

p.W213R

c.637T>A

1 paper

NM_000176.3

p.R214K

c.641G>A