Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.Q188*

c.562C>T

Surrounding Variants

1 paper

NM_000176.3

p.Q188Q

c.564A>G

1 paper

NM_000176.3

p.T190S

c.568A>T

1 paper

NM_000176.3

p.T190S

c.569C>G

1 paper

NM_000176.3

p.F191L

c.571T>C

2 papers

NM_000176.3

p.L183L

c.549G>A

1 paper

NM_000176.3

p.V181E

c.542T>A

1 paper

NM_000176.3

p.Q195*

c.583C>T

1 paper

NM_000176.3

p.D196Y

c.586G>T

1 paper

NM_000176.3

p.N180D

c.538A>G

1 paper

NM_000176.3

p.D196A

c.587A>C

8 papers

NM_000176.3

p.E198*

c.592G>T

1 paper

NM_000176.3

p.N177N

c.531C>T