Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.T176S

c.527C>G

Surrounding Variants

1 paper

NM_000176.3

p.T176S

c.526A>T

2 papers

NM_000176.3

p.N177S

c.530A>G

1 paper

NM_000176.3

p.N177N

c.531C>T

1 paper

NM_000176.3

p.T174P

c.520A>C

1 paper

NM_000176.3

p.N180D

c.538A>G

1 paper

NM_000176.3

p.G172V

c.515G>T

1 paper

NM_000176.3

p.V181E

c.542T>A

2 papers

NM_000176.3

p.L183L

c.549G>A

1 paper

NM_000176.3

p.Q167*

c.499C>T

1 paper

NM_000176.3

p.S165A

c.493T>G

1 paper

NM_000176.3

p.S164delFs

c.491delG

1 paper

NM_000176.3

p.Q188*

c.562C>T