Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.S132A

c.394T>G

Surrounding Variants

1 paper

NM_000176.3

p.R131K

c.392G>A

1 paper

NM_000176.3

p.N130Y

c.388A>T

1 paper

NM_000176.3

p.N130D

c.388A>G

2 papers

NM_000176.3

p.L129F

c.385C>T

1 paper

NM_000176.3

p.P136fs

c.406_407fs

2 papers

NM_000176.3

p.P139P

c.417C>A

1 paper

NM_000176.3

p.E124K

c.370G>A

1 paper

NM_000176.3

p.E123E

c.369A>G

1 paper

NM_000176.3

p.K140N

c.420G>T

1 paper

NM_000176.3

p.K140N

c.420G>C

3 papers

NM_000176.3

p.E123*

c.367G>T

1 paper

NM_000176.3

p.E123K

c.367G>A