Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.P105A

c.313C>G

Surrounding Variants

1 paper

NM_000176.3

p.F104L

c.312C>A

1 paper

NM_000176.3

p.Q106L

c.317A>T

14 papers

NM_000176.3

p.G103E

c.308G>A

1 paper

NM_000176.3

p.Q107insFs

c.319_320insT

1 paper

NM_000176.3

p.D101A

c.302A>C

1 paper

NM_000176.3

p.N100S

c.299A>G

1 paper

NM_000176.3

p.G99E

c.296G>A

7 papers

NM_000176.3

p.L112F

c.334C>T

1 paper

NM_000176.3

p.V97A

c.290T>C

1 paper

NM_000176.3

p.S113A

c.337T>G

1 paper

NM_000176.3

p.K96E

c.286A>G

1 paper

NM_000176.3

p.T95fs

c.283_284fs