Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.E92K

c.274G>A

Surrounding Variants

1 paper

NM_000176.3

p.E92D

c.276G>T

1 paper

NM_000176.3

p.G91V

c.272G>T

1 paper

NM_000176.3

p.E92fs

c.274_275fs

1 paper

NM_000176.3

p.G91A

c.272G>C

1 paper

NM_000176.3

p.T93A

c.277A>G

1 paper

NM_000176.3

p.M90I

c.270G>C

2 papers

NM_000176.3

p.T93I

c.278C>T

1 paper

NM_000176.3

p.T93K

c.278C>A

1 paper

NM_000176.3

p.E94K

c.280G>A

1 paper

NM_000176.3

p.E94V

c.281A>T

1 paper

NM_000176.3

p.T95A

c.283A>G

1 paper

NM_000176.3

p.T95fs

c.283_284fs