Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_000176.3

p.N72D

c.214A>G

Surrounding Variants

1 paper

NM_000176.3

p.S71I

c.212G>T

2 papers

NM_000176.3

p.A73T

c.217G>A

2 papers

NM_000176.3

p.A73V

c.218C>T

1 paper

NM_000176.3

p.Q74*

c.220C>T

1 paper

NM_000176.3

p.S69S

c.207A>T

1 paper

NM_000176.3

p.Q74fs

c.220_221fs

2 papers

NM_000176.3

p.G68A

c.203G>C

1 paper

NM_000176.3

p.P76T

c.226C>A

1 paper

NM_000176.3

p.P76Q

c.227C>A

1 paper

NM_000176.3

p.P76P

c.228A>T

1 paper

NM_000176.3

p.D77N

c.229G>A

1 paper

NM_000176.3

p.K67E

c.199A>G