Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000176.3

p.D55N

c.163G>A

Surrounding Variants

1 paper

NM_000176.3

p.S54L

c.161C>T

1 paper

NM_000176.3

p.S54T

c.160T>A

1 paper

NM_000176.3

p.S54fs

c.160_161fs

1 paper

NM_000176.3

p.Q58E

c.172C>G

1 paper

NM_000176.3

p.A51A

c.153T>C

7 papers

NM_000176.3

p.Q58H

c.174G>C

1 paper

NM_000176.3

p.A51V

c.152C>T

1 paper

NM_000176.3

p.R59*

c.175C>T

1 paper

NM_000176.3

p.R59G

c.175C>G

1 paper

NM_000176.3

p.V50D

c.149T>A

2 papers

NM_000176.3

p.L48L

c.144G>C

1 paper

NM_000176.3

p.L62L

c.186G>A