Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_000176.3

p.F29L

c.87C>A

Surrounding Variants

9 papers

NM_000176.3

p.F29L

c.87C>G

2 papers

NM_000176.3

p.Y30H

c.88T>C

9 papers

NM_000176.3

p.F29L

c.85T>C

1 paper

NM_000176.3

p.Y30F

c.89A>T

1 paper

NM_000176.3

p.Y30C

c.89A>G

1 paper

NM_000176.3

p.D28E

c.84C>A

1 paper

NM_000176.3

p.D28G

c.83A>G

1 paper

NM_000176.3

p.M27insFs

c.79_80insA

2 papers

NM_000176.3

p.M27T

c.80T>C

2 papers

NM_000176.3

p.T32N

c.95C>A

2 papers

NM_000176.3

p.L33I

c.97C>A

2 papers

NM_000176.3

p.L33R

c.98T>G