Varaico: Literature-Extracted Genetic Variants

NRG1

532 papers

RefSeq Summary

The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variet...

Pfam Domains

EGFaa 28–66UCSCEGF-like domain

I-setaa 36–129UCSCImmunoglobulin I-set domain

Neuregulinaa 113–275UCSCNeuregulin intracellular region

EGFaa 182–220UCSCEGF-like domain

Gene Aliases

HGNC Name

neuregulin 1

HGNC Previous Symbols

HGL; NRG1-IT2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_013964.5

p.M139I

c.417G>A

Surrounding Variants

3 papers

NM_013964.5

p.M139I

c.417G>C

3 papers

NM_013964.5

p.M139I

c.417G>T

1 paper

NM_013964.5

p.M139T

c.416T>C

1 paper

NM_013964.5

p.A141T

c.421G>A

1 paper

NM_013964.5

p.T137I

c.410C>T

1 paper

NM_013964.5

p.T143S

c.428C>G

1 paper

NM_013964.5

p.I135T

c.404T>C

1 paper

NM_013964.5

p.A146G

c.437C>G

1 paper

NM_013964.5

p.A146V

c.437C>T

1 paper

NM_013964.5

p.A146A

c.438A>G

1 paper

NM_013964.5

p.E151Splc

c.452-5T>C

1 paper

NM_013964.5

p.P153_I154insFs

c.459_460insG