neuropilin 2

VEGF165R2

Neuropilin-2

Vascular endothelial cell growth factor 165 receptor 2

C-terminal domain of neuropilin glycoprotein

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Jul 2021].

Varaico: Literature-Extracted Genetic Variants

NRP2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol