Varaico: Literature-Extracted Genetic Variants

NRP2

146 papers

RefSeq Summary

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secret...

Pfam Domains

CUBaa 28–139UCSCCUB domain

CUBaa 149–264UCSCCUB domain

F5_F8_type_Caa 292–424UCSCF5/8 type C domain

F5_F8_type_Caa 449–589UCSCF5/8 type C domain

MAMaa 646–800UCSCMAM domain, meprin/A5/mu

DUF3481aa 850–931UCSCC-terminal domain of neuropilin glycoprotein

Gene Aliases

HGNC Name

neuropilin 2

HGNC Alias Symbol

VEGF165R2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003872.3

p.R239H

c.716G>A

Surrounding Variants

2 papers

NM_003872.3

p.T242M

c.725C>T

1 paper

NM_003872.3

p.H250Y

c.748C>T

1 paper

NM_003872.3

p.L225fs

c.673_674fs

1 paper

NM_003872.3

p.P224T

c.670C>A

1 paper

NM_003872.3

p.V222A

c.665T>C

1 paper

NM_003872.3

p.A262delFs

c.785delC

2 papers

NM_003872.3

p.A262V

c.785C>T

1 paper

NM_003872.3

p.L266M

c.796C>A

2 papers

NM_003872.3

p.L272fs

c.814_815fs

2 papers

NM_003872.3

p.L272delFs

c.815delT

1 paper

NM_003872.3

p.E273*

c.817G>T

1 paper

NM_003872.3

p.V222A

c.665T>C