Varaico: Literature-Extracted Genetic Variants

OAS1

149 papers

RefSeq Summary

This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cel...

Pfam Domains

NTP_transf_2aa 37–134UCSCNucleotidyltransferase domain

OAS1_Caa 163–348UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 1

HGNC Previous Symbol

OIAS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016816.4

p.K42E

c.124A>G

Surrounding Variants

1 paper

NM_016816.4

p.G39G

c.117G>A

1 paper

NM_016816.4

p.G39E

c.116G>A

4 papers

NM_016816.4

p.R47*

c.139C>T

5 papers

NM_016816.4

p.R47Q

c.140G>A

1 paper

NM_016816.4

p.D35N

c.103G>A

1 paper

NM_016816.4

p.I34I

c.102T>C

1 paper

NM_016816.4

p.P52S

c.154C>T

2 papers

NM_016816.4

p.V55M

c.163G>A

1 paper

NM_016816.4

p.M28I

c.84G>A

1 paper

NM_016816.4

p.T24A

c.70A>G

1 paper

NM_016816.4

p.L21L

c.63G>A

1 paper

NM_016816.4

p.D18G

c.53A>G