Varaico: Literature-Extracted Genetic Variants

OAS1

149 papers

RefSeq Summary

This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cel...

Pfam Domains

NTP_transf_2aa 37–134UCSCNucleotidyltransferase domain

OAS1_Caa 163–348UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 1

HGNC Previous Symbol

OIAS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_016816.4

p.D75A

c.224A>C

Surrounding Variants

1 paper

NM_016816.4

p.D75E

c.225C>A

1 paper

NM_016816.4

p.D75E

c.225C>G

9 papers

NM_016816.4

p.A76V

c.227C>T

2 papers

NM_016816.4

p.D77A

c.230A>C

2 papers

NM_016816.4

p.R73*

c.217C>T

1 paper

NM_016816.4

p.G72S

c.214G>A

1 paper

NM_016816.4

p.V80I

c.238G>A

2 papers

NM_016816.4

p.T69N

c.206C>A

1 paper

NM_016816.4

p.T69I

c.206C>T

1 paper

NM_016816.4

p.T86S

c.256A>T

1 paper

NM_016816.4

p.S63F

c.188C>T

2 papers

NM_016816.4

p.G62A

c.185G>C