Varaico: Literature-Extracted Genetic Variants

OAS1

149 papers

RefSeq Summary

This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cel...

Pfam Domains

NTP_transf_2aa 37–134UCSCNucleotidyltransferase domain

OAS1_Caa 163–348UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 1

HGNC Previous Symbol

OIAS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016816.4

p.I102T

c.305T>C

Surrounding Variants

2 papers

NM_016816.4

p.R103K

c.308G>A

1 paper

NM_016816.4

p.R104G

c.310A>G

5 papers

NM_016816.4

p.I99V

c.295A>G

1 paper

NM_016816.4

p.Q105H

c.315G>C

1 paper

NM_016816.4

p.Q105H

c.315G>T

5 papers

NM_016816.4

p.C109Y

c.326G>A

1 paper

NM_016816.4

p.R95W

c.283C>T

1 paper

NM_016816.4

p.L92L

c.276A>G

1 paper

NM_016816.4

p.Q91E

c.271C>G

1 paper

NM_016816.4

p.S116delFs

c.346delT

2 papers

NM_016816.4

p.V117M

c.349G>A

1 paper

NM_016816.4

p.K118*

c.352A>T