Varaico: Literature-Extracted Genetic Variants

OAS1

149 papers

RefSeq Summary

This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cel...

Pfam Domains

NTP_transf_2aa 37–134UCSCNucleotidyltransferase domain

OAS1_Caa 163–348UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 1

HGNC Previous Symbol

OIAS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016816.4

p.G337A

c.1010G>C

Surrounding Variants

1 paper

NM_016816.4

p.W335_D336insFs

c.1005_1006ins7

1 paper

NM_016816.4

p.W343C

c.1029G>C

1 paper

NM_016816.4

p.W343C

c.1029G>T

1 paper

NM_016816.4

p.I344T

c.1031T>C

1 paper

NM_016816.4

p.N328S

c.983A>G

1 paper

NM_016816.4

p.L327P

c.980T>C

1 paper

NM_016816.4

p.A325D

c.974C>A

1 paper

NM_016816.4

p.G309D

c.926G>A

1 paper

NM_016816.4

p.N307I

c.920A>T

3 papers

NM_016816.4

p.P301L

c.902C>T

1 paper

NM_016816.4

p.I298N

c.893T>A

4 papers

NM_016816.4

p.V297G

c.890T>G