Varaico: Literature-Extracted Genetic Variants

OAS1

149 papers

RefSeq Summary

This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cel...

Pfam Domains

NTP_transf_2aa 37–134UCSCNucleotidyltransferase domain

OAS1_Caa 163–348UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 1

HGNC Previous Symbol

OIAS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001032409.3

p.G361R

c.1081G>C

Surrounding Variants

1 paper

NM_001032409.3

p.G361R

c.1081G>A

1 paper

NM_016816.4

p.Q390*

c.1168C>T

1 paper

NM_016816.4

p.A385V

c.1154C>T

10 papers

NM_016816.4

p.R361T

c.1082G>C

2 papers

NM_001032409.3

p.G397R

c.1189G>A

2 papers

NM_001032409.3

p.G397R

c.1189G>C

7 papers

NM_016816.4

p.A352T

c.1054G>A

3 papers

NM_016816.4

p.L346_A347Splc

c.1039-1G>A

1 paper

NM_016816.4

p.L346_A347Splc

c.1038+577G>A

1 paper

NM_016816.4

p.I344T

c.1031T>C

1 paper

NM_016816.4

p.W343C

c.1029G>C

1 paper

NM_016816.4

p.W343C

c.1029G>T