Varaico: Literature-Extracted Genetic Variants

OAS2

89 papers

RefSeq Summary

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine...

Pfam Domains

OAS1_Caa 153–338UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

NTP_transf_2aa 373–474UCSCNucleotidyltransferase domain

OAS1_Caa 496–685UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 2

HGNC Previous Names

2'-5'-oligoadenylate synthetase 2 (69-71 kD); 2'-5'-oligoadenylate synthetase 2, 69/71kDa

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002535.3

p.K164T

c.491A>C

Surrounding Variants

1 paper

NM_002535.3

p.K164N

c.492A>C

1 paper

NM_002535.3

p.K164E

c.490A>G

1 paper

NM_002535.3

p.K164N

c.492A>T

1 paper

NM_002535.3

p.L163L

c.489C>G

1 paper

NM_002535.3

p.S166F

c.497C>T

1 paper

NM_002535.3

p.S166S

c.498C>T

1 paper

NM_002535.3

p.L167S

c.500T>C

1 paper

NM_002535.3

p.K169E

c.505A>G

1 paper

NM_002535.3

p.P157T

c.469C>A

1 paper

NM_002535.3

p.A172A

c.516C>T

1 paper

NM_002535.3

p.S173G

c.517A>G

2 papers

NM_002535.3

p.N154S

c.461A>G