Varaico: Literature-Extracted Genetic Variants

OAS2

89 papers

RefSeq Summary

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine...

Pfam Domains

OAS1_Caa 153–338UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

NTP_transf_2aa 373–474UCSCNucleotidyltransferase domain

OAS1_Caa 496–685UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 2

HGNC Previous Names

2'-5'-oligoadenylate synthetase 2 (69-71 kD); 2'-5'-oligoadenylate synthetase 2, 69/71kDa

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002535.3

p.L328F

c.984A>T

Surrounding Variants

1 paper

NM_002535.3

p.L328F

c.984A>C

1 paper

NM_002535.3

p.P329T

c.985C>A

1 paper

NM_002535.3

p.S321P

c.961T>C

1 paper

NM_002535.3

p.T320A

c.958A>G

1 paper

NM_002535.3

p.K312N

c.936A>C

1 paper

NM_002535.3

p.K312N

c.936A>T

1 paper

NM_002535.3

p.L311delFs

c.933delG

1 paper

NM_002535.3

p.L311V

c.931C>G

1 paper

NM_002535.3

p.Q309*

c.925C>T

1 paper

NM_002535.3

p.G303R

c.907G>A

1 paper

NM_002535.3

p.D296G

c.887A>G

1 paper

NM_002535.3

p.D293A

c.878A>C