Varaico: Literature-Extracted Genetic Variants

OAS2

89 papers

RefSeq Summary

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine...

Pfam Domains

OAS1_Caa 153–338UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

NTP_transf_2aa 373–474UCSCNucleotidyltransferase domain

OAS1_Caa 496–685UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 2

HGNC Previous Names

2'-5'-oligoadenylate synthetase 2 (69-71 kD); 2'-5'-oligoadenylate synthetase 2, 69/71kDa

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002535.3

p.R393Q

c.1178G>A

Surrounding Variants

1 paper

NM_002535.3

p.R393W

c.1177C>T

1 paper

NM_002535.3

p.V392A

c.1175T>C

1 paper

NM_002535.3

p.Q390L

c.1169A>T

1 paper

NM_002535.3

p.R374H

c.1121G>A

1 paper

NM_002535.3

p.R374P

c.1121G>C

1 paper

NM_002535.3

p.I372V

c.1114A>G

1 paper

NM_002535.3

p.Q357Q

c.1071G>A

1 paper

NM_002535.3

p.Q357P

c.1070A>C

1 paper

NM_002535.3

p.L356V

c.1066C>G

1 paper

NM_002535.3

p.K353R

c.1058A>G

1 paper

NM_002535.3

p.F351I

c.1051T>A

1 paper

NM_002535.3

p.K350N

c.1050G>C