Varaico: Literature-Extracted Genetic Variants

OAS2

89 papers

RefSeq Summary

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine...

Pfam Domains

OAS1_Caa 153–338UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

NTP_transf_2aa 373–474UCSCNucleotidyltransferase domain

OAS1_Caa 496–685UCSC2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

Gene Aliases

HGNC Name

2'-5'-oligoadenylate synthetase 2

HGNC Previous Names

2'-5'-oligoadenylate synthetase 2 (69-71 kD); 2'-5'-oligoadenylate synthetase 2, 69/71kDa

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002535.3

p.L542F

c.1626A>T

Surrounding Variants

1 paper

NM_002535.3

p.L542F

c.1626A>C

1 paper

NM_002535.3

p.D541_L542insFs

c.1623_1624insT

1 paper

NM_002535.3

p.K547N

c.1641G>C

1 paper

NM_002535.3

p.K547N

c.1641G>T

4 papers

NM_002535.3

p.R535Q

c.1604G>A

1 paper

NM_002535.3

p.Y550F

c.1649A>T

1 paper

NM_002535.3

p.R533C

c.1597C>T

2 papers

NM_002535.3

p.F524L

c.1572C>A

2 papers

NM_002535.3

p.F524L

c.1572C>G

2 papers

NM_002535.3

p.F524L

c.1570T>C

1 paper

NM_002535.3

p.P516Q

c.1547C>A

1 paper

NM_002535.3

p.V502I

c.1504G>A