Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002539.3

p.K448E

c.1342A>G

Surrounding Variants

5 papers

NM_002539.3

p.K448*

c.1342A>T

1 paper

NM_002539.3

p.R449C

c.1345C>T

1 paper

NM_002539.3

p.A452T

c.1354G>A

1 paper

NM_002539.3

p.A452V

c.1355C>T

1 paper

NM_002539.3

p.A452E

c.1355C>A

1 paper

NM_002539.3

p.A455V

c.1364C>T

3 papers

NM_002539.3

p.P438_V439delFs

c.1313_1316del4

1 paper

NM_002539.3

p.S456L

c.1367C>T

1 paper

NM_002539.3

p.A457A

c.1371T>C

2 papers

NM_002539.3

p.P438fs

c.1312_1313fs

1 paper

NM_002539.3

p.S458G

c.1372A>G

2 papers

NM_002539.3

p.T436_L437Fs

c.1307_1311delinsTFs