Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002539.3

p.Q419*

c.1255C>T

Surrounding Variants

1 paper

NM_002539.3

p.Q418*

c.1252C>T

3 papers

NM_002539.3

p.W414_Q421delFs

c.1242_1263del22

3 papers

NM_002539.3

p.W414*

c.1242G>A

3 papers

NM_002539.3

p.W414*

c.1241G>A

1 paper

NM_002539.3

p.P423P

c.1269C>T

2 papers

NM_002539.3

p.D424N

c.1270G>A

2 papers

NM_002539.3

p.W414Splc

c.1242-2A>G

1 paper

NM_002539.3

p.P426A

c.1276C>G

1 paper

NM_002539.3

p.P427A

c.1279C>G

1 paper

NM_002539.3

p.E428K

c.1282G>A

1 paper

NM_002539.3

p.E428A

c.1283A>C

1 paper

NM_002539.3

p.E430A

c.1289A>C