Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002539.3

p.N398S

c.1193A>G

Surrounding Variants

1 paper

NM_002539.3

p.Y406F

c.1217A>T

1 paper

NM_002539.3

p.Y389D

c.1165T>G

1 paper

NM_002539.3

p.G387D

c.1160G>A

1 paper

NM_002539.3

p.G387S

c.1159G>A

1 paper

NM_002539.3

p.S410L

c.1229C>T

1 paper

NM_002539.3

p.E384A

c.1151A>C

1 paper

NM_002539.3

p.F383L

c.1149T>G

1 paper

NM_002539.3

p.F383L

c.1149T>A

1 paper

NM_002539.3

p.F383L

c.1147T>C

4 papers

NM_002539.3

p.W414fs

c.1240_1241fs

3 papers

NM_002539.3

p.W414Splc

c.1241+1G>T

2 papers

NM_002539.3

p.W414insFs

c.1240_1241dupTG