Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002539.3

p.E308A

c.923A>C

Surrounding Variants

1 paper

NM_002539.3

p.S309L

c.926C>T

1 paper

NM_002539.3

p.D307G

c.920A>G

1 paper

NM_002539.3

p.S309delFs

c.926delG

1 paper

NM_002539.3

p.V322I

c.964G>A

1 paper

NM_002539.3

p.V322D

c.965T>A

1 paper

NM_002539.3

p.N327H

c.979A>C

2 papers

NM_002539.3

p.Y331S

c.992A>C

1 paper

NM_002539.3

p.D332Y

c.994G>T

2 papers

NM_002539.3

p.D332E

c.996C>G

2 papers

NM_002539.3

p.D332E

c.996C>A

1 paper

NM_002539.3

p.H335Y

c.1003C>T

1 paper

NM_002539.3

p.S303A

c.907T>G