Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002539.3

p.E274A

c.821A>C

Surrounding Variants

1 paper

NM_002539.3

p.R277S

c.831A>T

1 paper

NM_002539.3

p.R277S

c.831A>C

2 papers

NM_002539.3

p.R270*

c.808A>T

1 paper

NM_002539.3

p.G268R

c.802G>C

1 paper

NM_002539.3

p.G268R

c.802G>A

2 papers

NM_002539.3

p.T285M

c.854C>T

1 paper

NM_002539.3

p.A287G

c.860C>G

2 papers

NM_002539.3

p.A258V

c.773C>T

1 paper

NM_002539.3

p.I290_I291insFs

c.870_871insGT

1 paper

NM_002539.3

p.P257L

c.770C>T

1 paper

NM_002539.3

p.K293R

c.878A>G

1 paper

NM_002539.3

p.V254I

c.760G>A