Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002539.3

p.Q129R

c.386A>G

Surrounding Variants

1 paper

NM_002539.3

p.T132T

c.396T>G

1 paper

NM_002539.3

p.N125D

c.373A>G

2 papers

NM_002539.3

p.D134A

c.401A>C

1 paper

NM_002539.3

p.E136V

c.407A>T

1 paper

NM_002539.3

p.Y122N

c.364T>A

1 paper

NM_002539.3

p.V137D

c.410T>A

1 paper

NM_002539.3

p.Q119H

c.357A>T

1 paper

NM_002539.3

p.Q119H

c.357A>C

1 paper

NM_002539.3

p.S118F

c.353C>T

1 paper

NM_002539.3

p.K141R

c.422A>G

1 paper

NM_002539.3

p.A143V

c.428C>T

1 paper

NM_002539.3

p.K115I

c.344A>T