Varaico: Literature-Extracted Genetic Variants

ODC1

160 papers

RefSeq Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimu...

Pfam Domains

Orn_DAP_Arg_deCaa 40–387UCSCPyridoxal-dependent decarboxylase, C-terminal sheet domain

Orn_Arg_deC_Naa 45–281UCSCPyridoxal-dependent decarboxylase, pyridoxal binding domain

Gene Aliases

HGNC Name

ornithine decarboxylase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002539.3

p.E94A

c.281A>C

Surrounding Variants

1 paper

NM_002539.3

p.Q96R

c.287A>G

1 paper

NM_002539.3

p.S100R

c.298A>C

1 paper

NM_002539.3

p.S100I

c.299G>T

1 paper

NM_002539.3

p.S100R

c.300T>G

1 paper

NM_002539.3

p.S100R

c.300T>A

1 paper

NM_002539.3

p.P104S

c.310C>T

1 paper

NM_002539.3

p.P104H

c.311C>A

1 paper

NM_002539.3

p.Q99_P104del0

c.296_310del15

1 paper

NM_002539.3

p.P105P

c.315A>T

7 papers

NM_002539.3

p.E106K

c.316G>A

1 paper

NM_002539.3

p.K115I

c.344A>T

1 paper

NM_002539.3

p.K115R

c.344A>G