Varaico: Literature-Extracted Genetic Variants

OGFR

61 papers

RefSeq Summary

The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety...

Pfam Domains

OGFr_Naa 86–293UCSCOpioid growth factor receptor (OGFr) conserved region

OGFr_IIIaa 517–536UCSCOpioid growth factor receptor disordered repeat

OGFr_IIIaa 537–556UCSCOpioid growth factor receptor disordered repeat

OGFr_IIIaa 557–576UCSCOpioid growth factor receptor disordered repeat

OGFr_IIIaa 577–596UCSCOpioid growth factor receptor disordered repeat

OGFr_IIIaa 597–616UCSCOpioid growth factor receptor disordered repeat

Gene Aliases

HGNC Name

opioid growth factor receptor

HGNC Alias Symbol

7-60

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007346.4

p.S539S

c.1617G>A

Surrounding Variants

3 papers

NM_007346.4

p.R545S

c.1633C>A

1 paper

NM_007346.4

p.G551R

c.1651G>A

1 paper

NM_007346.4

p.G551R

c.1651G>C

3 papers

NM_007346.4

p.S525R

c.1575C>A

3 papers

NM_007346.4

p.S525R

c.1575C>G

3 papers

NM_007346.4

p.S525R

c.1573A>C

1 paper

NM_007346.4

p.A555fs

c.1663_1664fs

2 papers

NM_007346.4

p.E556K

c.1666G>A

1 paper

NM_007346.4

p.E556fs

c.1666_1667fs

6 papers

NM_007346.4

p.S557T

c.1670G>C

2 papers

NM_007346.4

p.S519L

c.1556C>T

1 paper

NM_007346.4

p.P515T

c.1543C>A