Varaico: Literature-Extracted Genetic Variants

OGG1

1,056 papers

RefSeq Summary

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase ...

Pfam Domains

OGG_Naa 25–141UCSC8-oxoguanine DNA glycosylase, N-terminal domain

HhH-GPDaa 142–296UCSCHhH-GPD superfamily base excision DNA repair protein

HhH-GPDaa 142–299UCSCHhH-GPD superfamily base excision DNA repair protein

Gene Aliases

HGNC Name

8-oxoguanine DNA glycosylase

HGNC Alias Symbols

HMMH; HOGG1; OGH1; MUTM

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002542.6

p.L33R

c.98T>G

Surrounding Variants

1 paper

NM_002542.6

p.L33P

c.98T>C

1 paper

NM_002542.6

p.R34G

c.100C>G

1 paper

NM_002542.6

p.E32E

c.96G>A

1 paper

NM_002542.6

p.E32G

c.95A>G

1 paper

NM_002542.6

p.R34R

c.102C>A

1 paper

NM_002542.6

p.L35V

c.103C>G

1 paper

NM_002542.6

p.S31F

c.92C>T

1 paper

NM_002542.6

p.L35L

c.105G>T

2 papers

NM_002542.6

p.S31P

c.91T>C

2 papers

NM_002542.6

p.D36N

c.106G>A

1 paper

NM_002542.6

p.R30L

c.89G>T

2 papers

NM_002542.6

p.R30S

c.88C>A