Varaico: Literature-Extracted Genetic Variants

OGG1

1,056 papers

RefSeq Summary

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase ...

Pfam Domains

OGG_Naa 25–141UCSC8-oxoguanine DNA glycosylase, N-terminal domain

HhH-GPDaa 142–296UCSCHhH-GPD superfamily base excision DNA repair protein

HhH-GPDaa 142–299UCSCHhH-GPD superfamily base excision DNA repair protein

Gene Aliases

HGNC Name

8-oxoguanine DNA glycosylase

HGNC Alias Symbols

HMMH; HOGG1; OGH1; MUTM

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002542.6

p.L39V

c.115C>G

Surrounding Variants

1 paper

NM_002542.6

p.L39M

c.115C>A

1 paper

NM_002542.6

p.L39L

c.115C>T

1 paper

NM_002542.6

p.P40T

c.118C>A

1 paper

NM_002542.6

p.P40S

c.118C>T

1 paper

NM_002542.6

p.V38I

c.112G>A

1 paper

NM_002542.6

p.V38F

c.112G>T

1 paper

NM_002542.6

p.P40H

c.119C>A

1 paper

NM_002542.6

p.P40L

c.119C>T

1 paper

NM_002542.6

p.L37M

c.109C>A

1 paper

NM_002542.6

p.L37V

c.109C>G

1 paper

NM_002542.6

p.L37L

c.109C>T

1 paper

NM_002542.6

p.D36E

c.108C>A