Varaico: Literature-Extracted Genetic Variants

OGG1

1,056 papers

RefSeq Summary

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase ...

Pfam Domains

OGG_Naa 25–141UCSC8-oxoguanine DNA glycosylase, N-terminal domain

HhH-GPDaa 142–296UCSCHhH-GPD superfamily base excision DNA repair protein

HhH-GPDaa 142–299UCSCHhH-GPD superfamily base excision DNA repair protein

Gene Aliases

HGNC Name

8-oxoguanine DNA glycosylase

HGNC Alias Symbols

HMMH; HOGG1; OGH1; MUTM

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002542.6

p.S211N

c.632G>A

Surrounding Variants

1 paper

NM_002542.6

p.A212P

c.634G>C

1 paper

NM_002542.6

p.A210V

c.629C>T

3 papers

NM_002542.6

p.R213*

c.637C>T

1 paper

NM_002542.6

p.S209S

c.627T>C

1 paper

NM_002542.6

p.R213Q

c.638G>A

1 paper

NM_002542.6

p.V208G

c.623T>G

1 paper

NM_002542.6

p.V208M

c.622G>A

1 paper

NM_002542.6

p.V208delFs

c.623delT

1 paper

NM_002542.6

p.Y207*

c.621C>A

1 paper

NM_002542.6

p.Y207*

c.621C>G

1 paper

NM_002542.6

p.Y207C

c.620A>G

1 paper

NM_002542.6

p.Y207delFs

c.621delC