Varaico: Literature-Extracted Genetic Variants

OGG1

1,056 papers

RefSeq Summary

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase ...

Pfam Domains

OGG_Naa 25–141UCSC8-oxoguanine DNA glycosylase, N-terminal domain

HhH-GPDaa 142–296UCSCHhH-GPD superfamily base excision DNA repair protein

HhH-GPDaa 142–299UCSCHhH-GPD superfamily base excision DNA repair protein

Gene Aliases

HGNC Name

8-oxoguanine DNA glycosylase

HGNC Alias Symbols

HMMH; HOGG1; OGH1; MUTM

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002542.6

p.S320R

c.958A>C

Surrounding Variants

1 paper

NM_002542.6

p.S320G

c.958A>G

1 paper

NM_002542.6

p.F319L

c.957C>A

1 paper

NM_002542.6

p.F319L

c.957C>G

2 papers

NM_002542.6

p.S320T

c.959G>C

1 paper

NM_002542.6

p.S320R

c.960T>A

1 paper

NM_002542.6

p.S320R

c.960T>G

1 paper

NM_002542.6

p.F319L

c.955T>C

1 paper

NM_002542.6

p.L318L

c.954G>C

1 paper

NM_002542.6

p.L318Q

c.953T>A

5 papers

NM_002542.6

p.D322N

c.964G>A

1 paper

NM_002542.6

p.D322A

c.965A>C

1 paper

NM_002542.6

p.D322D

c.966C>T