Varaico: Literature-Extracted Genetic Variants

Gene:OPRM1
Variant:p.F125L

OPRM1

1,057 papers

RefSeq Summary

This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta...

Pfam Domains

7tm_1aa 87–338UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

opioid receptor mu 1

HGNC Alias Symbols

MOR1; MOP

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000914.5
p.F125L
c.375C>A
Surrounding Variants
1 paper
NM_000914.5
p.F125L
c.375C>G
1 paper
NM_000914.5
p.F125L
c.373T>C
1 paper
NM_000914.5
p.P124P
c.372C>T
1 paper
NM_000914.5
p.S127G
c.379A>G
1 paper
NM_000914.5
p.S127S
c.381T>C
1 paper
NM_000914.5
p.S127_V128ins1
c.381_382insATC
1 paper
NM_000914.5
p.L123L
c.367C>T
1 paper
NM_000914.5
p.V128V
c.384G>T
1 paper
NM_000914.5
p.L131L
c.391C>T
1 paper
NM_000914.5
p.A119G
c.356C>G
1 paper
NM_000914.5
p.A117V
c.350C>T
1 paper
NM_000914.5
p.T134I
c.401C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."