Varaico: Literature-Extracted Genetic Variants

ORC5

41 papers

RefSeq Summary

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC b...

Pfam Domains

AAA_16aa 7–155UCSCAAA ATPase domain

ORC5_lidaa 204–271UCSCORC5, lid domain

ORC5_Caa 302–431UCSCOrigin recognition complex (ORC) subunit 5 C-terminus

Gene Aliases

HGNC Name

origin recognition complex subunit 5

HGNC Previous Symbol

ORC5L

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002553.4

p.K346T

c.1037A>C

Surrounding Variants

1 paper

NM_002553.4

p.T323I

c.968C>T

1 paper

NM_002553.4

p.L315_N319del0

c.944_955del12

1 paper

NM_002553.4

p.L359V

c.1075C>G

2 papers

NM_002553.4

p.N379S

c.1136A>G