oxysterol binding protein like 8

OSBP10

ORP8

MST120

MSTP120

oxysterol binding protein-like 8

Oxysterol-binding protein-related protein 8

ORP-8

OSBP-related protein 8

This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].

Varaico: Literature-Extracted Genetic Variants

OSBPL8

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols