Varaico: Literature-Extracted Genetic Variants

OSMR

124 papers

RefSeq Summary

This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleuk...

Pfam Domains

LIFR_D2aa 28–138UCSCLeukemia inhibitory factor receptor D2 domain

LIF-R_Ig-likeaa 151–234UCSCLeukemia inhibitory factor receptor, Ig-like domain

LIFR_D4aa 237–330UCSCLeukemia inhibitory factor receptor D4 domain

fn3aa 530–609UCSCFibronectin type III domain

fn3aa 623–732UCSCFibronectin type III domain

Gene Aliases

HGNC Name

oncostatin M receptor

HGNC Alias Symbols

OSMRB; OSMRbeta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003999.3

p.V506I

c.1516G>A

Surrounding Variants

1 paper

NM_003999.3

p.I507_A508insG

c.1519_1523ins3

15 papers

NM_003999.3

p.G513D

c.1538G>A

2 papers

NM_003999.3

p.G513A

c.1538G>C

1 paper

NM_003999.3

p.S492N

c.1475G>A

1 paper

NM_003999.3

p.P487A

c.1459C>G

1 paper

NM_003999.3

p.P526P

c.1578C>T

2 papers

NM_003999.3

p.E527K

c.1579G>A

2 papers

NM_003999.3

p.L483L

c.1449C>G

1 paper

NM_003999.3

p.G463R

c.1387G>A

1 paper

NM_003999.3

p.G463R

c.1387G>C

3 papers

NM_003999.3

p.N462S

c.1385A>G

1 paper

NM_003999.3

p.S457*

c.1370C>A