Varaico: Literature-Extracted Genetic Variants

OSMR

124 papers

RefSeq Summary

This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleuk...

Pfam Domains

LIFR_D2aa 28–138UCSCLeukemia inhibitory factor receptor D2 domain

LIF-R_Ig-likeaa 151–234UCSCLeukemia inhibitory factor receptor, Ig-like domain

LIFR_D4aa 237–330UCSCLeukemia inhibitory factor receptor D4 domain

fn3aa 530–609UCSCFibronectin type III domain

fn3aa 623–732UCSCFibronectin type III domain

Gene Aliases

HGNC Name

oncostatin M receptor

HGNC Alias Symbols

OSMRB; OSMRbeta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_003999.3

p.V631L

c.1891G>C

Surrounding Variants

4 papers

NM_003999.3

p.V631L

c.1891G>T

2 papers

NM_003999.3

p.D627E

c.1881C>A

2 papers

NM_003999.3

p.D627E

c.1881C>G

1 paper

NM_003999.3

p.A624A

c.1872T>C

1 paper

NM_003999.3

p.D647Y

c.1939G>T

3 papers

NM_003999.3

p.D647V

c.1940A>T

1 paper

NM_003999.3

p.Y660fs

c.1978_1979fs

1 paper

NM_003999.3

p.Y660delFs

c.1979_1980delAC

1 paper

NM_003999.3

p.P673S

c.2017C>T

10 papers

NM_003999.3

p.I691T

c.2072T>C

1 paper

NM_003999.3

p.D692G

c.2075A>G

9 papers

NM_003999.3

p.P694L

c.2081C>T