Varaico: Literature-Extracted Genetic Variants

Gene:P2RX7
Variant:p.C363S

P2RX7

488 papers

RefSeq Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the for...

Pfam Domains

P2X_receptoraa 11–390UCSCATP P2X receptor
P2RX7_Caa 400–592UCSCP2X purinoreceptor 7 intracellular domain

Gene Aliases

HGNC Name

purinergic receptor P2X 7

HGNC Alias Symbols

P2X7; MGC20089

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002562.6
p.C363S
c.1088G>C
Surrounding Variants
1 paper
NM_002562.6
p.C363S
c.1087T>A
1 paper
NM_002562.6
p.C362S
c.1085G>C
1 paper
NM_002562.6
p.C362S
c.1084T>A
2 papers
NM_002562.6
p.N361S
c.1082A>G
1 paper
NM_002562.6
p.H366N
c.1096C>A
26 papers
NM_002562.6
p.H366D
c.1096C>G
1 paper
NM_002562.6
p.Y358*
c.1074C>A
1 paper
NM_002562.6
p.Y358*
c.1074C>G
2 papers
NM_002562.6
p.Y358F
c.1073A>T
3 papers
NM_002562.6
p.P369S
c.1105C>T
55 papers
NM_002562.6
p.T357S
c.1070C>G
55 papers
NM_002562.6
p.T357S
c.1069A>T
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